ω-Conotoxin MVIIC

Code:
4283-v
Name:
ω-Conotoxin MVIIC
Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2 (Disulfide bonds between Cys1-Cys16, Cys8-Cys20, and Cys15-Cys26)
(M.W. 2749.3) C106H178N40O32S7
P/Q-type Ca2+ Channel Blocker
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main

Purity:
≧98.0% (HPLC)
Storage:
-20 ℃
Source:
Marine Snail, Conus magus

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. D.R. Hillyard, V.D. Monje, I.M. Mintz, B.P. Bean, L. Nadasdi, J. Ramachandran, G. Miljanich, A. Azimi-Zoonooz, J.M. McIntosh, L.J. Crutz, J.S. Imperial, and B.M. Olivera, Neuron, 9, 69 (1992). (Original)
  2. M.E. Adams, R.A. Myers, J.S. Imperial, and B.M. Olivera, Biochemistry, 32, 12566 (1993). (Pharmacol.)
  3. W.A. Sather, T. Tanabe, J.-F. Zhang, Y. Mori, M.E. Adams, and R.W. Tsien, Neuron, 11, 291 (1993). (Pharmacol.)
  4. D.B. Wheeler, A. Randall, and R.W. Tsien, Science, 264, 107 (1994). (Pharmacol.)
  5. B.M. Olivera,W.R. Gray, R. Zeikus, J.M. McIntosh, J. Varga, J. Rivier, V. De Santos, and L.J. Cruz, Science, 230, 1338 (1985). (Review)
  6. W.R. Gray, B.M. Olivera, and L.J. Cruz, Annu. Rev. Biochem., 57, 665 (1988). (Review)
  7. R.A. Myers, L.J. Cruz, J.E. Rivier, and B.M. Olivera, Chem. Rev., 93, 1923 (1993). (Review)
  8. B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)

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