Phosphoramidon

Code:
4082-v
Name:
Phosphoramidon
N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan
(Sodium Salt)
(M.W. 543.50) C23H34N3O10P
Inhibitor for Thermolysin, Neutral Endopeptidase-24.11(ANP Degradation Enzyme), and Endothelin Converting Enzyme
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Purity:
≧90.0% (HPLC), TLC single spot
Other Name:
Phosphoramidon disodium salt
ホスホラミドン
Storage:
-20 ℃
Production:
Microbial Product

Solubility: H2O (1 mM)

more information

Structure:
structure of Phosphoramidon
Category:
Enzyme Inhibitors

reference

  1. H. Suda, T. Aoyagi, T. Takeuchi, and H. Umezawa, J. Antibiotics, 26, 621 (1973). (Original)
  2. S.L. Stephenson and A.J. Kenny, Biochem. J., 243, 183 (1987). (Pharmacol.)
  3. B.P. Roques and A. Beaumont, Trends Pharmacol. Sci., 11, 245 (1990). (Review)
  4. Y. Matsumura, K. Hisaki, M. Takaoka, and S. Morimoto, Eur. J. Pharmacol., 185, 103 (1990). (Pharmacol.)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

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