Ac-Tyr-Val-Ala-Asp-H (aldehyde)

Code:
3165-v
Name:
Ac-Tyr-Val-Ala-Asp-H (aldehyde)
Ac-YVAD-CHO
Acetyl-L-tyrosyl-L-valyl-L-alanyl-L-aspart-1-al
(M.W. 492.52) C23H32N4O8
Inhibitor for Caspase-1
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Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (10 mM)

more information

Structure:
structure of Ac-Tyr-Val-Ala-Asp-H (aldehyde)
Category:
Enzyme Inhibitors

reference

  1. N.A. Thornberry, H.G. Bull, J.R. Calaycay, K.T. Chapman, A.D. Howard, M.J. Kostura, D.K. Miller, S.M. Molineaux, J.R. Weidner, J. Aunins, K.O. Elliston, J.M. Ayala, F.J. Casano, J. Chin, G.J.-F. Ding, L.A. Egger, E.P. Gaffney, G. Limjuco, O.C. Palyha, S.M. Raju, A.M. Rolando, J.P. Salley, T.-T. Yamin, T.D. Lee, J.E. Shively, M. MacCross, R.A. Mumford, J.A. Schmidt, and M.J. Tocci, Nature, 356, 768 (1992).
  2. S.M. Molineaux, F.J. Casano, A.M. Rolando, E.P. Peterson, G. Limjuco, J. Chin, P.R. Griffin, J.R. Calaycay, G.J.-F. Ding, T.-T. Yamin, O.C. Palyha, S. Luell, D. Fletcher, D.K. Miller, A.D. Howard, N.A. Thornberry, and M.J. Kostura, Proc. Natl. Acad. Sci. USA, 90, 1809 (1993).
  3. M. Enari, R.V. Talanian, W.W. Wong, and S. Nagata, Nature, 380, 723 (1996).
  4. M. Garcia-Calvo, E.P. Peterson, B. Leiting, R. Ruel, D.W. Nicholson, and N.A. Thornberry, J. Biol. Chem., 273, 32608 (1998).
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

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