{"id":3472,"date":"2016-02-02T09:31:18","date_gmt":"2016-02-02T00:31:18","guid":{"rendered":"https:\/\/www.peptide.co.jp\/en\/?p=3472"},"modified":"2023-08-29T10:18:06","modified_gmt":"2023-08-29T01:18:06","slug":"3558","status":"publish","type":"post","link":"https:\/\/www.peptide.co.jp\/en\/new-product\/3558.html","title":{"rendered":"Novel Cancer Imaging Probe; 2-NBDLG"},"content":{"rendered":"

\"23003_en_2-NBDLG_Fig-1\"<\/p>\n

2-NBDG (code 23002-v) has been widely utilized for monitoring D-glucose uptake in a variety of mammalian cells1)<\/sup>. 2-NBDLG (code 23003-v), an antipode of 2-NBDG, was initially developed as the control substrate derived from L-glucose which is not used as major source of energy2, 3)<\/sup>.
\nSurprisingly, 2-NBDLG uptake into spheroid-forming MIN6 insulinoma was found out by Yamada et al.4, 5)<\/sup>. Moreover, Onoe et al. showed that a high contrast between a tumor cell (C6 glioma) and a normal one in tumor model mouse can be obtained by administration of 2-NBDLG4)<\/sup>.
\nImaging method using 2-NBDLG is expected as a new diagnostics of cancers.
\n\u3000
\n\u3000<\/p>\n\n\n\n\n\n
Code<\/td>\nCompound<\/td>\nQuantity<\/td>\n<\/tr>\n
23002-v <\/a><\/td>\n2-NBDG<\/td>\n0.5 mg vial<\/td>\n<\/tr>\n
23003-v <\/a><\/td>\n2-NBDLG<\/td>\n0.5 mg vial<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Feel free to contact us if you have any questions.<\/a><\/Div><\/p>\n
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  1. Nature Protocols<\/i>, 2<\/B>, 753 (2007). DOI: 10.1038\/nprot.2007.76<\/a> (Protocols for Measurement)<\/i><\/li>\n
  2. Tetrahedron Lett<\/i>, 49<\/B>, 6876 (2008). DOI: 10.1016\/j.tetlet.2008.09.089<\/a> (Chem. Synthesis)<\/i><\/li>\n
  3. Bioorg. Med. Chem. Lett<\/i>, 21<\/B>, 4088 (2011).<\/li>\n
  4. Patent WO 2012133688 A1.<\/li>\n
  5. Human Cell<\/i>, 29<\/B>, 37 (2016). DOI: 10.1007\/s13577-015-0125-3<\/a><\/li>\n","protected":false},"excerpt":{"rendered":"

    2-NBDG (code 23002-v) has been widely utilized for monitoring D-glucose uptake in a variety of mammalian cells […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/posts\/3472"}],"collection":[{"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/comments?post=3472"}],"version-history":[{"count":9,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/posts\/3472\/revisions"}],"predecessor-version":[{"id":4930,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/posts\/3472\/revisions\/4930"}],"wp:attachment":[{"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/media?parent=3472"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/categories?post=3472"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.peptide.co.jp\/en\/wp-json\/wp\/v2\/tags?post=3472"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}