4416-s α-Defensin-3 (Human)

Code:
4416-s
Name:
α-Defensin-3 (Human)
HNP-3 (Human Neutrophil Peptide-3)
Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)
(M.W. 3486.0) C151H222N44O40S6
Antimicrobial Peptide
Package Price(Yen)
Vial 0.1 mg 20,000

main

Purity:
≧99.0% (HPLC)
Other Name:
α-ディフェンシン-3
α-デフェンシン-3
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
136661-76-2
Category:
Biologically Active Peptides

reference

  1. T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation)
  2. M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure)
  3. C.E. Mackewicz, J. Yuan, P. Tran, L. Diaz, E. Mack, M.E. Selsted, and J.A. Levy, AIDS, 17, F23 (2003). (Pharmacol.; Anti?HIV?1 Activity)
  4. F.T. Lundy, D.F. Orr, J.R. Gallagher, P. Maxwell, C. Shaw, S.S. Napier, C.G. Cowan, P.-J. Lamey, and J.J. Marley, Oral Oncol., 40, 139 (2004). (Pharmacol.; Role in Tumor Invasion)
  5. X.-M. Fang, Q. Shu, Q.-X. Chen, M. Book, H.-G. Sahl, A. Hoeft, and F. Stuber, Eur. J. Clin. Invest., 33, 82 (2003). (Histochem.; Regulation of Expression)
  6. R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; α-Defensin in Gastrointestinal Tract)
  7. S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
  8. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  9. M. Zasloff, Nature, 415, 389 (2002). (Review)
  10. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  11. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
  12. Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)