4320-v E-64-c

Code:
4320-v
Name:
E-64-c
[(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (3-methylbutyl)amide
(M.W. 314.38) C15H26N2O5
Inhibitor for Thiol Protease (Cathepsin B/H/L and Calpain)
Package Price(Yen)
Vial 5 mg 10,000

main

Purity:
≧98.0% (HPLC)
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (10 mM)

more information

Structure:
structure of E-64-c
CAS Registry Number:
76684-89-4
Category:
Enzyme Inhibitors

reference

  1. S. Hashida, T. Towatari, E. Kominami, and N. Katunuma, J. Biochem., 88, 1805 (1980). (Original; IC50)
  2. M. Tamai, K. Hanada, T. Adachi, K. Oguma, K. Kashiwagi, S. Omura, and M. Ohzeki, J. Biochem., 90, 255 (1981). (Chem. Structure & Biochem.)
  3. A.J. Barrett, A.A. Kembhavi, M.A. Brown, H. Kirschke, C.G. Knight, M. Tamai, and K. Hanada, Biochem. J., 201, 189 (1982). (Biochem.)
  4. K. Suzuki, J. Biochem., 93, 1305 (1983). (Biochem.)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).