4311-v α-Conotoxin ImI

Code:
4311-v
Name:
α-Conotoxin ImI
Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2 (Disulfide bonds between Cys2-Cys8 and Cys3-Cys12)
(M.W. 1351.6) C52H78N20O15S4
Blocker for Nicotinic Acetylcholine Receptor in Central Nervous System
Package Price(Yen)
Vial 0.5 mg 25,000

main

Purity:
≧99.0% (HPLC)
Storage:
-20 ℃
Source:
Marine Snail, Conus imperialis
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
156467-85-5
Category:
Biologically Active Peptides

reference

  1. J.M. McIntosh, D. Yoshikami, E. Mahe, D.B. Nielsen, J.E. Rivier, W.R. Gray, and B.M. Olivera, J. Biol. Chem., 269, 16733 (1994). (Original)
  2. D.S. Johnson, J. Martinez, A.B. Elgoyhen, S.F. Heinemann, and J.M. McIntosh, Mol. Pharmacol., 48, 194 (1995). (Pharmacol.)
  3. E.F.R. Pereira, M. Alkondon, J.M. McIntosh, and E.X. Albuquerque, J. Pharmacol. Exp. Ther., 278, 1472 (1996). (Pharmacol.; Competitive Antagonist)
  4. B.M. Olivera,W.R. Gray, R. Zeikus, J.M. McIntosh, J. Varga, J. Rivier, V. De Santos, and L.J. Cruz, Science, 230, 1338 (1985). (Review)
  5. W.R. Gray, B.M. Olivera, and L.J. Cruz, Annu. Rev. Biochem., 57, 665 (1988). (Review)
  6. R.A. Myers, L.J. Cruz, J.E. Rivier, and B.M. Olivera, Chem. Rev., 93, 1923 (1993). (Review)
  7. B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)