4295-s Uroguanylin Isomer A (Human)

Code:
4295-s
Name:
Uroguanylin Isomer A (Human)
Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bonds between Cys4-Cys12 and Cys7-Cys15)
(Trifluoroacetate Form)
(M.W. 1667.9) C64H102N18O26S4
Guanylate Cyclase C Activator
Package Price(Yen)
Vial 0.1 mg 9,000

main

Purity:
≧95.0% (HPLC)
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
154525-25-4
Category:
Biologically Active Peptides

reference

  1. T. Kita, C.E. Smith, K.F. Fok, K.L. Duffin, W.M. Moore, P.J. Karabatsos, J.F. Kachur, F.K. Hamra, N.V. Pidhorodeckyj, L.R. Forte, and M.G. Currie, Am. J. Physiol., 266, F342 (1994). (Original)
  2. M. Nakazato, H. Yamaguchi, H. Kinoshita, K. Kangawa, H. Matsuo, N. Chino, and S. Matsukura, Biochem. Biophys. Res. Commun., 220, 586 (1996). (Biologically Active / Inactive isomer)
  3. H. Kinoshita, S. Fujimoto, M. Nakazato, N. Yokota, Y. Date, H. Yamaguchi, S. Hisanaga, and T. Eto, Kidney Int., 52, 1028 (1997). (Urine/Plasma Level; Renal Disease)
  4. N. Chino, S. Kubo, T. Kitani, T. Yoshida, R. Tanabe, Y. Kobayashi, M. Nakazato, K. Kangawa, and T. Kimura, FEBS Lett., 421, 27 (1998). (Biochem.; Topological Isomers)
  5. N.G. Moss, D.A. Riguera, R.M. Solinga,M.M. Kessler, D.P. Zimmer,W.J. Arendshorst, M.G. Currie, and M.F. Goy, Hypertension, 53, 867 (2009). (Natriuretic Activity of Topological Isomers)
  6. L.R. Forte and M.G. Currie, FASEB J., 9, 643 (1995). (Review)
  7. L.R. Forte, X.H. Fan, and F.K. Hamra, Am. J. Kidney Dis., 28, 296 (1996). (Review)
  8. L.R. Forte, Pharmacol. Ther., 104, 137 (2004). (Review)