3218-v (Z-Leu-Leu-NHCH2)2CO

Code:
3218-v
Name:
(Z-Leu-Leu-NHCH2)2CO
(Z-LL)2 Ketone
1,3-Bis[(benzyloxycarbonyl-L-leucyl-L-leucyl)amino]acetone
(M.W. 809.00) C43H64N6O9
Inhibitor for Signal Peptide Peptidase
Package Price(Yen)
Vial 5 mg 10,000

main

Purity:
≧99.0% (HPLC)
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (10 mM)

more information

Structure:
structure of (Z-Leu-Leu-NHCH2)2CO
CAS Registry Number:
313664-40-3
Category:
Enzyme Inhibitors

reference

  1. A. Weihofen, M.K. Lemberg, H.L. Ploegh, M. Bogyo, and B. Martoglio, J. Biol. Chem., 275, 30951 (2000). (Original)
  2. A. Weihofen, K. Binns, M.K. Lemberg, K. Ashman, and B. Martoglio, Science, 296, 2215 (2002). (Signal Peptide Peptidase Inhibitor)
  3. A. Weihofen, M.K. Lemberg, E. Friedmann, H. Rueeger, A. Schmitz, P. Paganetti, G. Rovelli, and B. Martoglio, J. Biol. Chem., 278, 16528 (2003). (Signal Peptide Peptidase Inhibitory Activity)
  4. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).