4455-s Huwentoxin-IV

Code:
4455-s
Name:
Huwentoxin-IV
HWTX-IV
Glu-Cys-Leu-Glu-Ile-Phe-Lys-Ala-Cys-Asn-Pro-Ser-Asn-Asp-Gln-Cys-Cys-Lys-Ser-Ser-Lys-Leu-Val-Cys-Ser-Arg-Lys-Thr-Arg-Trp-Cys-Lys-Tyr-Gln-Ile-NH2 (Disulfide bonds between Cys2-Cys17, Cys9-Cys24, and Cys16-Cys31)
(Trifluoroacetate Form)
(M.W. 4106.8) C174H278N52O51S6
Neuronal Tetrodotoxin-Sensitive Na+-Channel Blocker
Package Price(Yen)
Vial 0.1 mg 22,000

main

Purity:
≧97.0% (HPLC)
Storage:
-20 ℃
Source:
Chinese Bird Spider, Ornithoctonus huwena
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. K. Peng, Q. Shu, Z. Liu, and S. Liang, J. Biol. Chem., 277, 47564 (2002). (Original)
  2. J. Diao, Y. Lin, J. Tang, and S. Liang, Toxicon, 42, 715 (2003). (cDNA Seq)
  3. Y. Xiao, J.-P. Bingham, W. Zhu, E. Moczydlowski, S. Liang, and T.R. Cummins, J. Biol. Chem., 283, 27300 (2008). (Pharmacol.)
  4. Y. Xiao, X. Luo, F. Kuang, M. Deng, M. Wang, X. Zeng, and S. Liang, Toxicon, 51, 230 (2008). (Pharmacol.)