4416-s α-Defensin-3 (Human)

Code:
4416-s
Name:
α-Defensin-3 (Human)
HNP-3 (Human Neutrophil Peptide-3)
Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)
(M.W. 3486.0) C151H222N44O40S6
Antimicrobial Peptide
Package Price(Yen)
Vial 0.1 mg 20,000

main

Purity:
≧99.0% (HPLC)
Other Name:
α-ディフェンシン-3
α-デフェンシン-3
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
136661-76-2
Category:
Biologically Active Peptides

reference

  1. T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation)
  2. M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure)
  3. C.E. Mackewicz, J. Yuan, P. Tran, L. Diaz, E. Mack, M.E. Selsted, and J.A. Levy, AIDS, 17, F23 (2003). (Pharmacol.; Anti?HIV?1 Activity)
  4. F.T. Lundy, D.F. Orr, J.R. Gallagher, P. Maxwell, C. Shaw, S.S. Napier, C.G. Cowan, P.-J. Lamey, and J.J. Marley, Oral Oncol., 40, 139 (2004). (Pharmacol.; Role in Tumor Invasion)
  5. X.-M. Fang, Q. Shu, Q.-X. Chen, M. Book, H.-G. Sahl, A. Hoeft, and F. Stuber, Eur. J. Clin. Invest., 33, 82 (2003). (Histochem.; Regulation of Expression)
  6. R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; α-Defensin in Gastrointestinal Tract)
  7. S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
  8. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  9. M. Zasloff, Nature, 415, 389 (2002). (Review)
  10. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)