4340-s Muscarinic Toxin 7

Code:
4340-s
Name:
Muscarinic Toxin 7
MT7, MTX7, m1-toxin1
Leu-Thr-Cys-Val-Lys-Ser-Asn-Ser-Ile-Trp-Phe-Pro-Thr-Ser-Glu-Asp-Cys-Pro-Asp-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Arg-Trp-Gln-Tyr-Ile-Ser-Pro-Arg-Met-Tyr-Asp-Phe-Thr-Arg-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Lys-Ala-Glu-Tyr-Arg-Asp-Val-Ile-Asn-Cys-Cys-Gly-Thr-Asp-Lys-Cys-Asn-Lys (Disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys57, and Cys58-Cys63)
(M.W. 7472.4) C322H484N90O98S9
Specific Ligand for Muscarinic Acetylcholine Receptor-1 (M1)
Package Price(Yen)
Vial 0.1 mg 30,000

main

Purity:
≧96.0% (HPLC)
Storage:
-20 ℃
Source:
Green Mamba, Dendroaspis angusticeps
Production:
Synthetic Product

Solubility: H2O (50 μM)

more information

Category:
Biologically Active Peptides

reference

  1. A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997). (Original)
  2. H.Nishio, Y. Nishiuchi, T. Inui, K.N. Bradley, A.L. Harvey, and T. Kimura, Peptide Science 1999, 125 (2000). (S-S Bond)
  3. J.M.Carsi and L.T. Potter, Toxicon, 38, 187 (2000). (Original; m1-toxin1)
  4. Z. Gu, P. Zhong, and Z. Yan, J. Biol. Chem., 278, 17546 (2003). (Pharmacol; Inhibition of β -Amyloid signaling)
  5. K.N. Bradley, Pharmacol. Ther., 85, 87 (2000). (Review)
  6. L.T. Potter, Life Sci., 68, 2541 (2001). (Review)
  7. D. Servent and C. Fruchart-Gaillard, J. Neurochem., 109, 1193 (2009). (Review)
  8. E. Karlsson, M. Jolkkonen, E. Mulugeta, P. Onali, and A. Adem, Biochimie, 82, 793 (2000). (Review)