4271-s α-Defensin-1 (Human)

Code:
4271-s
Name:
α-Defensin-1 (Human)
HNP-1 (HNP: Human Neutrophil Peptide-1)
Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)
(M.W. 3442.0) C150H222N44O38S6
Antimicrobial Peptide/Chemoattractant for Monocytes
Package Price(Yen)
Vial 0.1 mg 20,000

main

Purity:
≧99.0% (HPLC)
Other Name:
Defensin Human Neutrophil Peptide - 1
α-ディフェンシン-1
α-デフェンシン-1
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
148093-65-6
Category:
Biologically Active Peptides

reference

  1. T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation)
  2. M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure)
  3. S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
  4. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  5. M. Zasloff, Nature, 415, 389 (2002). (Review)
  6. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  7. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
  8. Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)