4063-v Chymostatin

Code:
4063-v
Name:
Chymostatin
A Mixture of Type A, B, and C
[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-iminohexahydro-4(S)-pyrimidyl]-(S)-glycyl-X-phenylalaninalX: L-leucyl (Type A), L-valyl (Type B), L-isoleucyl (Type C)
Inhibitor for Chymotrypsin, Chymase, Papain, and Cathepsin B/G
Package Price(Yen)
Vial 0.5 mg 5,000

main

Other Name:
キモスタチン
Storage:
-20 ℃
Production:
Microbial Product

Solubility: DMSO (1 mM)

more information

CAS Registry Number:
9076-44-2
Category:
Enzyme Inhibitors

reference

  1. H. Umezawa, T. Aoyagi, H. Morishima, S. Kunimoto, M. Matsuzaki, M. Hamada, and T. Takeuchi, J. Antibiotics, 23, 425 (1970). (Original)
  2. K. Tatsuta, N. Mikami, K. Fujimoto, S. Umezawa, H. Umezawa, and T. Aoyagi, J. Antibiotics, 26, 625 (1973). (Chem. Structure)
  3. R.L. Stein and A.M. Strimpler, Biochemistry, 26, 2611 (1987). (Inhibitory Activity)
  4. L.A. Johnson, K.E. Moon, and M. Eisenberg, Biochim. Biophys. Acta, 953, 269 (1988). (Inhibitory Activity)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).