4063 Chymostatin

Code:
4063
Name:
Chymostatin
A Mixture of Type A, B, and C
[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-iminohexahydro-4(S)-pyrimidyl]-(S)-glycyl-X-phenylalaninalX: L-leucyl (Type A), L-valyl (Type B), L-isoleucyl (Type C)
Inhibitor for Chymotrypsin, Chymase, Papain, and Cathepsin B/G
Package Price(Yen)
Bulk 25 mg 18,000
Bulk 100 mg 57,000

main

Other Name:
キモスタチン
Storage:
-20 ℃
Production:
Microbial Product

more information

CAS Registry Number:
9076-44-2
Category:
Enzyme Inhibitors

reference

  1. H. Umezawa, T. Aoyagi, H. Morishima, S. Kunimoto, M. Matsuzaki, M. Hamada, and T. Takeuchi, J. Antibiotics, 23, 425 (1970). (Original)
  2. K. Tatsuta, N. Mikami, K. Fujimoto, S. Umezawa, H. Umezawa, and T. Aoyagi, J. Antibiotics, 26, 625 (1973). (Chem. Structure)
  3. R.L. Stein and A.M. Strimpler, Biochemistry, 26, 2611 (1987). (Inhibitory Activity)
  4. L.A. Johnson, K.E. Moon, and M. Eisenberg, Biochim. Biophys. Acta, 953, 269 (1988). (Inhibitory Activity)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).