Amyloid b- Protein (Human, 1- 40) [HCl Form]
HCl Form of Amyloid b-Protein (Human, 1-40)
Easily Convertible to b-Structure! Now available!!
Amyloid b-proteins (Abs) have been found as major plaque components in the brains of Alzheimer's disease patients. Recently, Kaneko et al.reported that the HCl form of Ab(1-40) takes b-structure within a few hours, and it shows neurotoxic activity. On the other hand, TFA salt takes >1 week to take on a b-structure under their experimental conditions [J. Neurochem.,65, 2585 (1995), ibid.,68, 438 (1997)].
We prepared the HCl form of Ab(1-40) following their procedure and confirmed their observations shown above.
Characteristics of our new product Ab(1-40) [HCl form] are as follows; 1) random coil when supplied, 2) conformational change to b-structure within 24 hours (by CD measurement under our conditions), and 3) significant neurotoxic activity under our determining conditions. For more detail, please contact us.
To perform the reproducible study in Alzheimer's disease research, we now offer Ab(1-40) [HCl Form] with the highest quality.
| Code | Compound | Quantity | Price: Yen |
| 4379-v | Amyloid b- Protein (Human, 1- 40) [HCl Form] | 0.5 mg vial | \20,000 |
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