Peptide Institute


Code	MOCAc-Substrates	Specificity

3216-v	MOCAc-Ala-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dnp)-NH₂	Fluorescence-Quenching Substrate for Proteinase A / Pepsin
3167-v	MOCAc-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH₂	Fluorescence-Quenching Substrate for Matrix Metalloproteinases
3168-v	MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂	Fluorescence-Quenching Substrate for Matrix Metalloproteinase-3 (Stromelysin 1)
3184-v	MOCAc-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-NH₂	Fluorescence-Quenching Substrate for Caspase-3
3200-v	MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-	Fluorescence-Quenching Substrate for Cathepsin D/E
3225-v	MOCAc-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-	Fluorescence-Quenching Substrate for Cathepsin E
3226-v	MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH₂	Fluorescence-Quenching Substrate for Matrix Metalloproteinases and ADAM-17 / Tumor Necrosis Factor Converting Enzyme (TACE)
3163-v	MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH₂	Fluorescence-Quenching Substrate for Matrix Metalloproteinase
3164-s	MOCAc-Pro-Leu-Gly	Reference Compound for MOCAc-type Fluorescence-Quenching Substrate
3212-v	MOCAc-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH₂	Fluorescence-Quenching Substrate Flanking
3183-v	MOCAc-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-NH₂	Fluorescence-Quenching Substrate for Caspase-1


Code	pNA-Substrates	Specificity

3068	Ala-pNA	Substrate for Aminopeptidase
3125	Boc-Leu-Ser-Thr-Arg-pNA^.AcOH^.H₂O	Substrate for Activated Protein C
3013	Bz-DL-Arg-pNA^.HCl	Substrate for Trypsin-like Protease
3057	Bz-L-Arg-pNA^.HCl	Substrate for Trypsin-like Protease / Papain
3015	Bz-Tyr-pNA	Substrate for Chymotrypsin
3129	Glt-Ala-Ala-Pro-Leu-pNA^.H₂O	Substrate for Pancreatic Elastase
3067	Glu-pNA^.H₂O
3074-v	Gly-Pro-pNA^.Tos	Substrate for X-Prolyl Dipeptidyl-Aminopeptidase
3014	Leu-pNA	Substrate for Aminipeptidase
3130	Pyr-Phe-Leu-pNA	Substrate for Thiol Protease
3071	Suc-Ala-Ala-Ala-pNA	Substrate for Elastase
3071-v	Suc-Ala-Ala-Ala-pNA	Substrate for Elastase
3117	Suc-Ala-Ala-pNA
3162-v	Suc-Ala-Leu-Pro-Phe-pNA	Substrate for PPIase (Peptidyl Prolyl cis-trans Isomerase)
3116	Suc-Ala-pNA
3118	Suc-Ala-Pro-Ala-pNA	Substrate for Elastase
3127	Z-Ala-Ala-Leu-pNA	Substrate for Subtilisin A and Serine Protease of Bacillus subtilis IFO3027
3111	Z-Gly-Gly-Leu-pNA	Substrate for Neutral Endopeptidase

Code	MCA-Substrates	Specificity

3220-v	Ac-Asp-Asn-Leu-Asp-MCA	Selective Substrate for Caspase-3 Designed by in silico Screening System
3193-v	Ac-Asp-Gln-Thr-Asp-MCA	Substrate for Caspase-7/3 (Deduced from the Cleavage Site of Focal Adhesion Kinase and Gelsolin)
3171-v	Ac-Asp-Glu-Val-Asp-MCA	Substrate for Caspase-3 (Apopain/CPP32/Yama)
3195-v	Ac-Ile-Glu-Thr-Asp-MCA	Substrate for Procaspase-3 Cleaving Enzyme (Caspase-8/ Caspase-6 and Granzyme B) (Deduced from the Cleavage Site of Procaspase-3)
3198-v	Ac-Leu-Glu-His-Asp-MCA	Substrate for Caspase-9
3185-v	Ac-Lys-Thr-Lys-Gln-Leu-Arg-MCA	Substrate for Hepatocyte Growth Factor-Activator (HGF-A)
3186-v	Ac-Trp-Glu-His-Asp-MCA	Substrate for Caspase-1 (ICE), Caspase-4 and Caspase-5
3161-v	Ac-Tyr-Val-Ala-Asp-MCA	Substrate for Caspase-1/4
3203-v	Ac-Val-Asp-Val-Ala-Asp-MCA	Substrate for Caspase-2
3181-v	Ac-Val-Glu-Ile-Asp-MCA	Substrate for Caspase-6
3201-v	Ala-Ala-Phe-MCA	Substrate for Tripeptidyl Peptidase II (Component of Giant Protease with Some Proteasome Function)
3147-v	Ala-MCA	Substrate for Aminopeptidase
3113-v	Arg-MCA	Substrate for Cathepsin H
3144-v	Boc-Ala-Gly-Pro-Arg-MCA	Substrate for ANP(Rat) Precursor Processing Enzyme
3155-v	Boc-Arg-Val-Arg-Arg-MCA	Substrate for Furin
3139-v	Boc-Asp(OBzl)-Pro-Arg-MCA	Substrate for a-Thrombin
3135-v	Boc-Gln-Ala-Arg-MCA	Substrate for Trypsin
3122-v	Boc-Gln-Arg-Arg-MCA	Substrate for Carboxyl Side of Paired Basic Residue Cleaving Enzyme
3136-v	Boc-Gln-Gly-Arg-MCA	Substrate for Factor XIIa
3115-v	Boc-Glu(OBzl)-Gly-Arg-MCA
3134-v	Boc-Glu(OBzl)-Ala-Arg-MCA	Substrate for Factor XIa
3105-v	Boc-Glu-Lys-Lys-MCA	Substrate for Plasmin
3142-v	Boc-Gly-Arg-Arg-MCA	Substrate for Carboxyl Side of Paired Basic Residue Cleaving Enzyme
3143-v	Boc-Gly-Lys-Arg-MCA	Substrate for Carboxyl Side of Paired Basic Residue Cleaving Enzyme
3094-v	Boc-Ile-Glu-Gly-Arg-MCA	Substrate for Factor Xa
3140-v	Boc-Leu-Arg-Arg-MCA	Substrate for Carboxyl Side of Paired Basic Residue Cleaving Enzyme
3102-v	Boc-Leu-Gly-Arg-MCA	Substrate for Horseshoe Crab Clotting Enzyme
3141-v	Boc-Leu-Lys-Arg-MCA	Substrate for Carboxyl Side of Paired Basic Residue Cleaving Enzyme
3112-v	Boc-Leu-Ser-Thr-Arg-MCA	Substrate for Activated Protein C
3106-v	Boc-Leu-Thr-Arg-MCA	Substrate for Factor VIIa-Tf
3107-v	Boc-Phe-Ser-Arg-MCA	Substrate for Trypsin, Tryptase, and 73K Protease
3104-v	Boc-Val-Leu-Lys-MCA	Substrate for Plasmin
3093-v	Boc-Val-Pro-Arg-MCA	Substrate for a-Thrombin
3092-v	Bz-Arg-MCA	Substrate for Trypsin
3154-v	Glt-Ala-Ala-Phe-MCA	Substrate for Chymotrypsin
3097-v	Glt-Gly-Arg-MCA	Substrate for Urokinase
3090-v	Gly-Pro-MCA	Substrate for X-Prolyl Dipeptidyl-Aminopeptidase
3091-v	Leu-MCA	Substrate for Aminopeptidase
3124-v	Lys-Ala-MCA	Substrate for Dipeptidyl-Aminopeptidase II
3132-v	Lys-MCA	Substrate for Aminopeptidase
3149-v	Met-MCA	Substrate for Aminopeptidase
3148-v	Phe-MCA	Substrate for Aminopeptidase
3096-v	Pro-Phe-Arg-MCA	Substrate for Pancreatic/Urinary Kallikrein, and Proteasome
3159-v	Pyr-Arg-Thr-Lys-Arg-MCA	Substrate for Furin
3145-v	Pyr-Gly-Arg-MCA	Substrate for TPA and Urokinase
3101-v	Pyr-MCA	Substrate for Pyroglutamyl Peptidase
3153-v	Suc(OMe)-Ala-Ala-Pro-Val-MCA	Substrate for Human Leukocyte and Porcine Pancreatic Elastase
3114-v	Suc-Ala-Ala-Pro-Phe-MCA	Substrate for Chymotrypsin
3133-v	Suc-Ala-Ala-Ala-MCA	Substrate for Elastase
3160-v	Suc-Ala-Glu-MCA	Substrate for Ingensin and Proteasome
3100-v	Suc-Ala-Pro-Ala-MCA	Substrate for Elastase
3110-v	Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-MCA	Substrate for Renin and Proteinase A
3222-v	Suc-D-Asp-MCA	Selective Substrate for D-Aspartyl Endopeptidase
3108-v	Suc-Gly-Pro-Leu-Gly-Pro-MCA	Substrate for Collagenase-like Peptidase
3109-v	Suc-Gly-Pro-MCA	Substrate for Post-Proline Cleaving Enzyme
3158-v	Suc-Ile-Ala-MCA	Substrate for Amyloid A4 Generating Enzyme
3150-v	Suc-Ile-Ile-Trp-MCA
3120-v	Suc-Leu-Leu-Val-Tyr-MCA	Substrate for Chymotrypsin, Ingensin / Proteasome and Calpain
3209-v	Z-Ala-Ala-Asn-MCA	Substrate for Legumain
3123-v	Z-Arg-Arg-MCA	Substrate for Cathepsin B
3208-v	Z-Gly-Pro-Arg-MCA	Substrate for Cathepsin K
3215-v	Z-His-Glu-Lys-MCA	Substrate for Lys-Gingipain
3176-v	Z-Leu-Arg-Gly-Gly-MCA	Substrate for Isopeptidase T
3210-v	Z-Leu-Arg-MCA	Substrate for Cathepsin K / S / V
3177-v	Z-Leu-Leu-Leu-MCA	Substrate for Proteasome
3179-v	Z-Leu-Leu-Glu-MCA	Substrate for Proteasome
3095-v	Z-Phe-Arg-MCA	Substrate for Plasma Kallikrein and Cathepsin B/L
3138-v	Z-Pyr-Gly-Arg-MCA	Substrate for Factor Xa
3156-v	Z-Val-Lys-Met-MCA	Substrate for Amyloid A4-generating enzyme and Proteasome
3211-v	Z-Val-Val-Arg-MCA	Substrate for Cathepsin S / L