Peptide Institute

Code:	4392-s
Name:	Hepcidin/LEAP- 1 (Human)
	Liver-Expressed Antimicrobial Peptide 1 (Human)
Storage:
Production:	Synthetic Product

Asp- Thr- His- Phe- Pro- Ile- Cys- Ile- Phe- Cys- Cys- Gly- Cys- Cys- His- Arg- Ser- Lys- Cys- Gly- Met- Cys- Cys- Lys- Thr
(Disulfide bonds between Cys⁷- Cys²³, Cys¹⁰- Cys¹³, Cys¹¹- Cys¹⁹, and Cys¹⁴- Cys²² [reference 4 below])

(M.W. 2789.40) C₁₁₃H₁₇₀N₃₄O₃₁S₉

Liver-Specific Antimicrobial Peptide / Iron-Regulatory Hormone

References:

A. Krause, S. Neitz, H.-J. M�gert, A. Schulz, W.-G. Forssmann, P. Schulz-Knappe, and K. Adermann,FEBS Lett.,480,147 (2000).(Original; LEAP-1)

C.H. Park, E.V. Valore, A.J. Waring, and T. Ganz,J. Biol. Chem.,276,7806 (2001).(Original; Hepcidin)

R.E.Fleming and W.S. Sly,Proc. Natl. Acad. Sci. U.S.A.,98,8160 (2001).(Regulation of Iron Homeostasis)

J. B. Jordan, L. Poppe, M. Haniu, T. Arvedson, R. Syed, V. Li, H. Kohno, H. Kim, P. D. Schnier, T. S. Harvey, L. P. Miranda, J. Cheetham, and B. J. Sasu,J. Biol. Chem.,284,24155 (2009).(S-S Bond)

Package	Price(Yen)
Vial 0.1 mg	18,000