Peptide Institute

Code:	4259-s
Name:	Kaliotoxin (1- 37)
Storage:
Production:	Synthetic Product
Source:	Scorpion, Androctonus mauretanicus mauretanicus

Gly- Val- Glu- Ile- Asn- Val- Lys- Cys- Ser- Gly- Ser- Pro- Gln- Cys- Leu- Lys- Pro- Cys- Lys- Asp- Ala- Gly- Met- Arg- Phe- Gly- Lys- Cys- Met- Asn- Arg- Lys- Cys- His- Cys- Thr- Pro
(Disulfide bonds between Cys⁸- Cys²⁸, Cys¹⁴- Cys³³, and Cys¹⁸- Cys³⁵)

(M.W. 4021.80) C₁₆₅H₂₇₁N₅₃O₄₈S₈

High Conductance Ca²⁺-activated K⁺ Channel Blocker

References:

M. Crest, G. Jacquet, M. Gola, H. Zerrouk, A. Benslimane, H. Rochat, P. Mansuelle, and M.-F. Martin-Eauclaire,J. Biol. Chem.,267,1640 (1992).(Original)

R. Romi, M. Crest, M. Gola, F. Sampieri, G. Jacquet, H. Zerrouk, P. Mansuelle, O. Sorokine, A.V. Dorsselaer, H. Rochat, M.-F. Martin-Eauclaire, and J.V. Rietschoten,J. Biol. Chem.,268,26302 (1993).(Chem. Synthesis & Pharmacol.)

F.R. Romi, S. Szendeffy, M.F. Martin-Eauclaire, H. Rochat, J.V. Rietschoten, M. Pons, and E. Giralt,Biochemistry,33,14256 (1994).(Unique Structure)

A.L. Harvey, H. Vatanpour, E.G. Rowan, S. Pinkasfeld, C. Vita, A. Menez, and M.-F. Martin-Eauclaire,Toxicon,33,425 (1995).(Pharmacol.)

Package	Price(Yen)
Vial 0.1 mg	22,000