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Lactacystin
- Code:
- 4368-v
- Name:
- Lactacystin
- N-Acetyl-S-{(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidine-2-carbonyl}-L-cysteine
- (M.W. 376.43) C15H24N2O7S
- Inhibitor for Proteasome
| Package | Price(Yen) | Availability |
|---|---|---|
| Vial 0.2 mg | 20,000 |
Ships within 1-3 business days |
| Bulk Request | ||
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- more information
- reference
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- Other Name:
- ラクタシスチン
- Storage:
- -20 ℃
- Production:
- Microbial Product
Solubility: H2O (1 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- S. Omura, T. Fujimoto, K. Otoguro, K. Matsuzaki, R. Moriguchi, H. Tanaka, and Y. Sasaki, J. Antibiotics, 44, 113 (1991). (Original)
- S. Omura, K. Matsuzaki, T. Fujimoto, K. Kosuge, T. Furuya, S. Fujita, and A. Nakagawa, J. Antibiotics, 44, 117 (1991). (Original; Chem. Structure)
- G. Fenteany, R.F. Standaert, W.S. Lane, S. Choi, E.J. Corey, and S.L. Schreiber, Science, 268, 726 (1995). (Biochem.; Proteasome Inhibition)
- S. Imajoh-Ohmi, T. Kawaguchi, S. Sugiyama, K. Tanaka, S. Omura, and H. Kikuchi, Biochem. Biophys. Res. Commun., 217, 1070 (1995). (Biochem.; Apoptotic Effect)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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